Robert Neville is a scientist who was unable to stop the spread of a terrible, incurable and manmade virus. In what is left of New York City and perhaps the world, the immune Neville is now the last human survivor.
For three years, Neville faithfully sends out daily radio messages, desperate to find any other survivors. He is not alone, as mutant victims of the plague — The Infected — lurk in the shadows watching Neville’s every move, waiting for him to make a fatal mistake. Quickly running out of time and outnumbered, Neville is driven to find a way to reverse the effects of the virus using his own immune blood. He is mankind’s last hope.